MITRE ATT&CK vs MITRE ATLAS: Do you know which framework applies to AI threats? As AI becomes part of enterprise environments, attackers are targeting more than endpoints and networks; they’re going after models, data, prompts, APIs, and AI pipelines. That’s where MITRE ATT&CK and MITRE ATLAS take different approaches. ATT&CK focuses on traditional enterprise, cloud, OT, and endpoint threats, while ATLAS maps adversarial tactics against AI/ML systems and LLM architectures. Different attack surfaces. Different playbooks. Different defenses.